Parex LPD 325 Tablets

Parex LPD 325 Tablets are a multi-symptom relief formula designed to alleviate cold, allergy, and flu symptoms effectively. Each tablet contains a scientifically balanced combination of:

• Paracetamol 325 mg – Provides fast-acting pain relief and fever reduction.
• Levocetirizine Dihydrochloride 5 mg – A potent antihistamine that relieves sneezing, runny nose, and itchy eyes.
• Dextromethorphan HBr 5 mg – Suppresses dry, irritating cough by acting on the brain’s cough center.
• Phenylephrine Hydrochloride 5 mg – A nasal decongestant that eases blocked sinuses and improves airflow.
• Caffeine (Anhydrous) 30 mg – Enhances the pain-relieving effect of paracetamol and reduces drowsiness.

Pharmacokinetics and Pharmacodynamics

• Paracetamol: Quickly absorbed; metabolized in the liver with analgesic and antipyretic action.
• Levocetirizine: Rapidly absorbed; blocks histamine H1 receptors, easing allergy symptoms.
• Dextromethorphan: Centrally suppresses the cough reflex through action on the medulla.
• Phenylephrine: Acts on alpha-adrenergic receptors to relieve nasal congestion.
• Caffeine: Stimulates the central nervous system and enhances the effect of paracetamol.

Dosage Information

• Adults: 1 tablet every 6–8 hours as needed.
• Maximum Daily Dose: Do not exceed 4 tablets in 24 hours.
• Always follow physician’s advice for dosage and duration.

Contraindications

• Known hypersensitivity to any component.
• Severe hepatic or renal impairment.
• Use of monoamine oxidase inhibitors (MAOIs) or other CNS depressants.
• Not recommended during pregnancy or breastfeeding without medical supervision.

Storage

• Store below 30°C in a dry place.
• Keep away from light and moisture.
• Keep out of reach of children.

Warnings and Precautions

• Avoid alcohol while taking this medication.
• Use with caution in patients with hypertension, diabetes, thyroid disorders, or glaucoma.
• Stop use and consult a healthcare professional if symptoms persist or worsen.
• Not intended for long-term use without medical guidance.