L-CET MX Tablets (Levocetirizine Dihydrochloride 5 mg + Montelukast Sodium 10 mg)

L-CET MX Tablets are an effective dual-action therapy for managing allergic rhinitis, seasonal allergies, and asthma-related symptoms. This combination tablet offers

• Levocetirizine Dihydrochloride (5 mg): A potent second-generation antihistamine that provides fast, long-lasting relief from sneezing, runny nose, and itchy eyes.
• Montelukast Sodium (10 mg): A leukotriene receptor antagonist that helps prevent inflammation, nasal congestion, and bronchoconstriction, making it useful in allergic asthma.

Together, they provide broad-spectrum allergy and respiratory symptom control.

Pharmacokinetics and Pharmacodynamics

• Levocetirizine: Rapidly absorbed, peak plasma levels at ~0.9 hours. Selectively blocks H1 receptors to reduce histamine-mediated allergic responses.
• Montelukast: Peak plasma concentration in 3–4 hours; acts by blocking leukotriene D4 at the cysteinyl leukotriene receptor, reducing bronchial inflammation and allergic symptoms.

Dosage Information

• Adults and Adolescents (≥15 years): One tablet daily in the evening, with or without food, or as directed by a physician.
• Route: Oral.

Contraindications

• Hypersensitivity to Levocetirizine, Montelukast, or any excipients
• Severe renal impairment (CrCl <10 mL/min)
• Not suitable for children under 15 years without physician supervision

Storage Instructions

• Store between 15–30°C
• Protect from moisture and light
• Keep out of children’s reach

Warnings and Precautions

• Use cautiously in patients with hepatic impairment or psychiatric disorders
• Avoid alcohol or other CNS depressants during treatment
• Discontinue immediately if hypersensitivity or adverse effects occur
• Not recommended for self-medication—consult a healthcare provider before use