Amorex-625 Tablets

Amorex-625 is a powerful combination antibiotic used to treat a wide range of bacterial infections. It pairs:

• Amoxicillin 500 mg – A broad-spectrum beta-lactam antibiotic that inhibits bacterial cell wall synthesis.
• Potassium Clavulanate 125 mg – A beta-lactamase inhibitor that protects amoxicillin from degradation, ensuring effectiveness against resistant bacteria.

This synergistic combination is especially effective against infections of the respiratory tract, urinary tract, skin, and soft tissues.

Pharmacokinetics

• Absorption: Rapid oral absorption; peak plasma levels within 1–2 hours.
• Distribution: Extensively distributed in body fluids and tissues.
• Metabolism & Excretion: Primarily excreted unchanged in urine; amoxicillin has a half-life of ~1 hour.

Pharmacodynamics

• Amoxicillin: Inhibits bacterial cell wall synthesis, leading to cell lysis.
• Clavulanate: Neutralizes beta-lactamase enzymes, overcoming bacterial resistance and restoring antibiotic effectiveness.

Dosage Information:

• Adults and Children >12 years: One tablet every 8–12 hours or as prescribed by a physician.
• Take with food to reduce gastrointestinal side effects.

Contraindications

• Known hypersensitivity to penicillins, cephalosporins, or any ingredient in the formulation.
• History of liver dysfunction or cholestatic jaundice associated with prior penicillin use.

Storage

• Store in a cool, dry place below 25°C.
• Protect from light and moisture.
• Keep out of reach of children.

Warnings and Precautions

• Use with caution in patients with liver or kidney impairment.
• Discontinue use immediately in the event of an allergic reaction (e.g., rash, anaphylaxis).
• Prolonged use may lead to secondary infections (superinfections).
• Avoid alcohol consumption during the treatment period.
• Always complete the full course of therapy and follow medical advice.