Aceparex Tablets(Aceclofenac 100 mg + Paracetamol 325 mg)

Aceparex is a fast-acting, dual-combination analgesic and anti-inflammatory tablet designed for effective relief from pain, fever, and inflammation. Each tablet contains:

• Aceclofenac (100 mg): A potent NSAID that reduces inflammation and pain by inhibiting COX enzymes and prostaglandin production.
• Paracetamol (325 mg): A widely trusted analgesic and antipyretic that enhances pain relief and lowers fever by acting on the central nervous system.

This synergistic combination offers quick and sustained relief in conditions like musculoskeletal pain, arthritis, backache, dental pain, and fever.

Pharmacokinetics

• Aceclofenac: Rapid oral absorption; peak plasma levels within 1–3 hours; metabolized in the liver; excreted mainly via urine.
• Paracetamol: Absorbed quickly; peak levels in 30 minutes–2 hours; liver metabolism; excreted in urine as conjugates.

Pharmacodynamics

• Aceclofenac: Suppresses COX-1 and COX-2 enzymes, reducing pain and inflammation.
• Paracetamol: Acts centrally to reduce fever and provide analgesic effects without significant GI irritation.

Dosage Information

• Recommended Dose: One tablet twice daily, preferably with or after food.
• Dosage may be adjusted by a healthcare provider based on patient condition and response.

Contraindications

• Hypersensitivity to Aceclofenac, Paracetamol, or NSAIDs
• Active peptic ulcer or gastrointestinal bleeding
• Severe hepatic, renal, or cardiac impairment
• Use during third trimester of pregnancy or during lactation

Storage

• Store below 25°C in a cool, dry place.
• Protect from moisture and direct sunlight.
• Keep out of reach of children.

Warnings and Precautions

• Avoid in patients with known NSAID-induced asthma or allergies.
• Long-term use may cause GI bleeding, liver toxicity, or kidney damage.
• Use cautiously in patients with liver or renal impairment.
• Do not consume alcohol during treatment.
• Discontinue and consult a doctor if symptoms persist or adverse effects occur.